First trimester prenatal diagnosis of cantrell’s pentalogy in a twin pregnancy

Methods A 31-year-old primigravid woman presented with a twin pregnancy at 14 weeks of gestation for evaluation of structural abnormalities in one co-twin. The marriage was non consanguineous. There was not history of genetic disorders or structural anomalies noted in the both parents. This was her first pregnancy and it was achieved by in vitro fertilization (ivf) and embryo transfer. One embryo was implanted and a monochorionic twin pregnancy was achieved. Ultrasound examinations were performed at 7 and 9 weeks of gestation. At 9 weeks' gestation one of the twins died. In our first evaluation the ultrasound revealed an alive co-twin with a large omphalocele containing herniated liver, spleen and bowel loops, ectopia cordis and increased nuchal translucency (NT: 3, 1 mm) at 14 weeks.